PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Acmella oleracea extract in mucoadhesive films showed topical anesthetic efficacy in mice [PMID:27626796]. In a randomized crossover clinical trial of 40 volunteers, jambu extract was investigated as a promising alternative for topical anesthesia of the buccal and palatal mucosa [PMID:41377174].
Acmella paniculata flower extracts (n-hexane and dichloromethane) acted as bactericidal agents against Streptococcus mutans [PMID:35774750].
Hydroethanolic extract and isolated spilanthol exhibited cytotoxicity against human gastric cancer cells [PMID:37300460].
Hexanic fractions rich in alkylamides promoted antinociceptive and anti-inflammatory effects in mouse models of neuropathic and postoperative pain [PMID:35659524].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36297745 (2022) — A Review of the Chemistry and Biological Activities of Acmella oleracea ("jambù", Asteraceae), with a View to the Development of Bioinsecticides and Acaricides. · Plants (Basel, Switzerland)
- 2.PMID: 33251347 (2020) — Comparison of powdered and fresh jambu (Acmella oleracea). · Heliyon
- 3.PMID: 41836524 (2026) — Exploring the Antibacterial Properties of Acmella Species: A Systematic Literature Review. · Drug design, development and therapy
- 4.PMID: 37048271 (2023) — Thermal Degradation of Carotenoids from Jambu Leaves (Acmella oleracea) during Convective Drying. · Foods (Basel, Switzerland)
- 5.PMID: 37111805 (2023) — Jambu Flower Extract (Acmella oleracea) Increases the Antioxidant Potential of Beer with a Reduced Alcohol Content.