PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Long-term treatment (12+ weeks) showed significant decreases in symptom scores and increases in maximum and average urine flow rates, though prostatic volume remained unchanged in the short term [PMID:7538904]. Other reviews note mixed efficacy results with significant confounders like poor product standardization [PMID:27180172]. In a comparative trial, tamsulosin and a combination of tamsulosin and cernitin were more effective than cernitin alone for urinary disturbance [PMID:12094707].
Cernitin pollen extract was used as add-on therapy to alpha-blockers, showing significant improvement in NIH-CPSI total, pain, and quality of life sub-scores at 12 weeks [PMID:32648985].
Administration of cernitin pollen extract for 30 days resulted in a significant mean decrease in serum PSA levels (-0.6 ± 1.4 ng/mL) [PMID:29577437]. However, a review of RCTs concluded that evidence for most dietary factors, including cernitin, is inadequate to recommend their use for down-regulating PSA in men with prostate cancer or increased risk [PMID:33003518].
A randomized, double-blind, placebo-controlled study investigated the efficacy of nonsolvent flower pollen extracts (Graminex RCT Fem UI and Graminex PollenBerry) on UI in healthy women over 24 weeks [PMID:39219633].
Dosage & administration
Evidence summary
PubMed sources
- 1.PMID: 35692639 (2022) — The complete chloroplast genome of weedy rye Secale cereale subsp. segetale. · Mitochondrial DNA. Part B, Resources
- 2.PMID: 16988347 (2006) — Rye (Secale cereale L.). · Methods in molecular biology (Clifton, N.J.)
- 3.PMID: 33003518 (2020) — Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials. · Nutrients
- 4.PMID: 27180172 (2016) — Phytotherapy for Benign Prostatic Hyperplasia. · Current urology reports
- 5.PMID: 32648985 (2020) — Comparison of cernitin pollen extract vs tadalafil therapy for refractory chronic prostatitis/chronic pelvic pain syndrome: A randomized, prospective study.