PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Linden flower infusion (2%) decreased serum marker enzymes AST and LDH and reduced MDA content compared to ethanol-only groups, suggesting hepatoprotective and antioxidant roles [PMID:24337514].
A hydroethanolic extract was administered orally at 4.5 mg/10 mL to evaluate therapeutic properties [PMID:33978005].
Hydroethanolic extracts showed antitumor activity against hepatocellular (173 µg/mL), cervical (195 µg/mL), breast (224 µg/mL), and lung (247 µg/mL) carcinoma cells [PMID:28164200].
Evidence summary
PubMed sources
- 1.PMID: 33385911 (2021) — Nutlets of Tilia cordata Mill. and Tilia platyphyllos Scop. - Source of bioactive compounds. · Food chemistry
- 2.PMID: 33434940 (2021) — Novel Piperidine and 3,4-dihydro-2H-pyrrole Alkaloids from Tilia platyphyllos and Tilia cordata Flowers. · Planta medica
- 3.PMID: 33978005 (2021) — Toxicological and anti-tumor effects of a linden extract (Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model. · Food & function
- 4.PMID: 31415913 (2019) — Comparative metabolomics of Tilia platyphyllos Scop. bracts during phenological development. · Phytochemistry
- 5.PMID: 24337514 (2014) — Hepatoprotective and antioxidant activity of linden (Tilia platyphyllos L.) infusion against ethanol-induced oxidative stress in rats.