PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Daily administration of 3.5g freeze-dried wheatgrass powder for 10 weeks significantly lowered total cholesterol, triacylglycerols, and Apolipoprotein B compared to control [PMID:28121470].
A wheatgrass diet (200 and 400 mg/kg) in streptozotocin-induced diabetic rats improved hyperglycemia, body weight, lipid profile, and biochemical indices (AST, ALT, GSH, GPx) [PMID:33547672].
Ethanolic wheatgrass extract (GM-T) improved serum liver enzyme activities, liver inflammation scores, steatosis, and obesity in mice fed choline-deficient or high-fat diets [PMID:30414175].
Methanolic extract (200 mg/kg) improved the estrous cycle, antioxidant status, and increased weight of the uterus and ovaries in BPA-fed rats [PMID:39600302].
Wheatgrass has demonstrated cytotoxic potential against breast cancer cell lines (MCF-7 and MDA-231) [PMID:37767028] and is suggested as an adjunct in various cancers, though evidence for colorectal cancer remains limited [PMID:38791211, 40511096].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37767028 (2023) — Modulation of wheatgrass (Triticum aestivum Linn) toxicity against breast cancer cell lines by simulated microgravity. · Current research in toxicology
- 2.PMID: 33547672 (2021) — Flavonoid-rich wheatgrass (Triticum aestivum L.) diet attenuates diabetes by modulating antioxidant genes in streptozotocin-induced diabetic rats. · Journal of food biochemistry
- 3.PMID: 30414175 (2019) — Triticum aestivum ethanolic extract improves non-alcoholic fatty liver disease in mice fed a choline-deficient or high-fat diet. · Journal of the science of food and agriculture
- 4.PMID: 38791211 (2024) — The Role of Wheatgrass in Colorectal Cancer: A Review of the Current Evidence. · International journal of molecular sciences
- 5.PMID: 39600302 (2024) — Methanolic extract of wheatgrass (Triticum aestivum L.) prevents BPA-induced disruptions in the ovarian steroidogenic pathway and alleviates uterine inflammation in Wistar rats.