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Andrographis paniculata
Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Andrographis may have antiplatelet effects that increase bleeding risk with warfarin.
Andrographolide inhibits PAF-induced platelet aggregation, adding to warfarin's anticoagulant effect.
Source: Natural Medicines Database · Reviewed April 2026
Andrographis + Warfarin (Coumadin): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Andrographis may have antiplatelet effects that increase bleeding risk with warfarin.
Andrographolide inhibits PAF-induced platelet aggregation, adding to warfarin's anticoagulant effect.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.