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Oenothera biennis
Moderate· limited-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Evening primrose oil may have mild anticoagulant properties that add to warfarin's effect.
GLA and its metabolites may inhibit platelet aggregation.
Source: Natural Medicines Database · Reviewed April 2026
Evening Primrose + Warfarin (Coumadin): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Evening primrose oil may have mild anticoagulant properties that add to warfarin's effect.
GLA and its metabolites may inhibit platelet aggregation.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.