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Oenothera biennis
Evening primrose is a wildflower native to North America whose seed oil is a rich source of gamma-linolenic acid (GLA), an omega-6 essential fatty acid. The oil has been widely used since the 1980s for women's health conditions and skin disorders. It plays an important role in prostaglandin synthesis and inflammatory regulation.
| Drug | Severity | Description |
|---|---|---|
| Phenothiazines (Chlorpromazine) | severe | Evening primrose oil may lower the seizure threshold, increasing seizure risk in patients taking phenothiazines. |
| Warfarin (Coumadin) | moderate | Evening primrose oil may have mild anticoagulant properties that add to warfarin's effect. |