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Actaea racemosa
Black cohosh is a perennial plant native to eastern North America, traditionally used by Native Americans for women's health conditions. It is one of the most researched herbs for menopausal symptoms and has been used in Europe for over 50 years as a menopause treatment. Its mechanism of action remains under investigation.
| Drug | Severity | Description |
|---|---|---|
| Hepatotoxic medications (general) | moderate | Black cohosh has been associated with rare cases of liver damage. Combining with other hepatotoxic drugs may increase liver injury risk. |
| Tamoxifen | moderate | Black cohosh may interact with tamoxifen in hormone-sensitive conditions. The nature of interaction is uncertain. |