This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Vitex agnus-castus
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
This herb may interact with medications you are taking. Review the interactions table below and consult your healthcare provider before use.
Vitex is the fruit of the chaste tree, native to the Mediterranean and Central Asia. It has been used for women's health for over 2,000 years. It acts on the pituitary gland to modulate prolactin and other hormones. Clinical evidence supports its use for PMS, menstrual irregularities, and certain fertility issues.
Vitex is the fruit of the chaste tree, native to the Mediterranean and Central Asia. It has been used for women's health for over 2,000 years. It acts on the pituitary gland to modulate prolactin and other hormones. Clinical evidence supports its use for PMS, menstrual irregularities, and certain fertility issues. Key active compounds include Agnuside, Casticin, Penduletin.
Agnuside, along with Casticin and Penduletin, are the primary bioactive compounds in Vitex. These compounds acts on pain pathways via anti-inflammatory and neuroactive effects.
Premenstrual syndrome (PMS)
Supported by clinical evidence; more large-scale trials would strengthen findings
Menstrual irregularities
Supported by clinical evidence; more large-scale trials would strengthen findings
Female infertility (luteal phase defect)
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Fibrocystic breast pain
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Menopausal symptoms
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Menstrual regulation
Based on traditional use; clinical evidence limited
Fertility support
Based on traditional use; clinical evidence limited
Lactation promotion
| Drug | Severity | Description |
|---|---|---|
| Dopamine agonists (Bromocriptine) | Moderate | Vitex has dopaminergic activity and may interact with dopamine-related medications. |
| Oral Contraceptives | Moderate | Vitex's hormonal effects may theoretically interfere with hormonal contraceptive effectiveness. |
Found an error or have a correction for Vitex?
Report an Issue →Based on traditional use; clinical evidence limited