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Vitex agnus-castus
Vitex is the fruit of the chaste tree, native to the Mediterranean and Central Asia. It has been used for women's health for over 2,000 years. It acts on the pituitary gland to modulate prolactin and other hormones. Clinical evidence supports its use for PMS, menstrual irregularities, and certain fertility issues.
| Drug | Severity | Description |
|---|---|---|
| Dopamine agonists (Bromocriptine) | moderate | Vitex has dopaminergic activity and may interact with dopamine-related medications. |
| Oral Contraceptives | moderate | Vitex's hormonal effects may theoretically interfere with hormonal contraceptive effectiveness. |