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This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Shatavari (Asparagus racemosus) is an Ayurvedic herb traditionally used to support female reproductive health and lactation [PMID:30000872, PMID:41055223].
Background
Asparagus racemosus, known as Shatavari, is a medicinal plant found in tropical and subtropical India and is distinct from the edible Asparagus officinalis [PMID:30000872, PMID:17240097]. It is described in Ayurveda as a rasayana herb and adaptogen used to increase non-specific resistance to stress [PMID:17240097].
Traditional uses
Traditionally used in Ayurveda for female reproductive health, as a galactogogue to increase breast milk, and for the treatment of gastric ulcers, dyspepsia, nervous disorders, inflammation, liver diseases, and certain infectious diseases [PMID:30000872, PMID:14515032, PMID:38725785].
Active compounds
The root contains steroidal saponins (specifically shatavarins I-VI), phytoestrogens, flavonoids, polyphenols, polysaccharides, mucilage, folic acid, sarsasapogenin, and alkaloids [PMID:30000872, PMID:40334116].
Mechanism of action
Shatavari exhibits adaptogenic, anti-inflammatory, and antioxidant properties [PMID:40334116, PMID:40454371]. It may target estrogen receptor alpha and show antiproliferative activity in T47D cancer cell lines [PMID:30580607]. In neuroprotection, it may lower oxidative stress, regulate neuroinflammation, and prevent amyloid-beta development [PMID:40454371].
Clinical evidence
Evidence BPostpartum Lactation
Controlled studies indicate increased serum prolactin, infant weight, greater milk volumes, and shorter times to breast fullness at 72 hours postpartum compared to placebo [PMID:30000872].
Evidence BMenopausal/Perimenopausal Symptoms
Standardized root extract has been evaluated for reducing vasomotor symptoms, improving hormonal balance, and decreasing Menopause Rating Scale (MRS) scores [PMID:40434025, PMID:41209045, PMID:41394012].
Evidence BPostmenopausal Muscle Function
Six weeks of supplementation improved handgrip strength and increased markers of myosin contractile function [PMID:38214710].
Evidence BPostmenopausal Vascular and Bone Health
Dose-dependent decrease in Menopause-Specific Quality of Life (MENQOL) scores and reflection index (RI) was observed [PMID:40347163].
Safety & adverse effects
Shatavari is generally described as having no significant adverse effects in clinical and preclinical settings [PMID:33689806].
Pregnancy & lactation
Traditionally used as a galactogogue [PMID:30000872]; however, pregnant and breastfeeding women are advised to consult healthcare professionals before use [PMID:40974515].
Dosage & administration
Clinical trials have utilized various dosages, including 200 mg/day [PMID:40434025], 300 mg twice daily [PMID:41055223], and 300 mg once daily [PMID:41209045]. No PubMed data available. Consult a healthcare provider.
Evidence summary
The evidence is primarily based on randomized controlled trials (Level B) and reviews (Level C), showing promise for lactation and menopausal symptom management, though some results for galactogogue activity are mixed [PMID:30000872].
PubMed sources
1.PMID: 30000872 (2006) — Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health. · Cureus
2.PMID: 38725785 (2024) — Efficacy and Safety of Shatavari Root Extract for the Management of Menopausal Symptoms: A Double-Blind, Multicenter, Randomized Controlled Trial. · Cureus
3.PMID: 14515032 (2003) — Asparagus racemosus--an update. · Indian journal of medical sciences
4.PMID: 41055223 (2025) — Shatavari (Asparagus racemosus Willd) root extract for postpartum lactation: A randomised, double-blind, placebo-controlled study. · Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
No direct government monograph is available for this herb. The content below is AI-generated and has not been verified against an authoritative government source. Use the search links to check official sources before relying on this information.
— A Standardized Asparagus Racemosus Root Extract Improves Hormonal Balance and Menstrual Health and Reduces Vasomotor Symptoms in Perimenopausal Women: A Randomized, Double-Blind, Placebo-Controlled Study.
· Journal of the American Nutrition Association
6.PMID: 41209045 (2025) — Efficacy and Safety of Shatavari (Asparagus racemosus) Root Extract for Perimenopause: Randomized, Double-Blind, Placebo-Controlled Study. · International journal of women's health
7.PMID: 38214710 (2024) — Shatavari supplementation in postmenopausal women alters the skeletal muscle proteome and pathways involved in training adaptation. · European journal of nutrition
8.PMID: 40334116 (2025) — An Updated Insight on the Chemistry, Ethnobotany, and Health Benefits of Asparagus racemosus (Shatavari): With a Special Emphasis on Shatavarin IV. · Journal of the American Nutrition Association
9.PMID: 40454371 (2025) — Exploring the neuroprotective role of Asparagus racemosus (Shatavari) in Alzheimer's disease: mechanisms, evidence, and future directions. · 3 Biotech
10.PMID: 41394012 (2025) — Efficacy and safety of Shatavari root extract (Asparagus racemosus) for menopausal symptoms: a randomized, double-blind, three-arm, placebo-controlled study. · Frontiers in reproductive health
11.PMID: 30580607 (2020) — Asparagus racemosus (Shatavari) targeting estrogen receptor α: - An in-vitro and in-silico mechanistic study. · Natural product research
12.PMID: 40974515 (2025) — Shatavari (Asparagus racemosus): A Promising Ally for Fertility. · Current nutrition reports
13.PMID: 29635127 (2018) — Impact of stress on female reproductive health disorders: Possible beneficial effects of shatavari (Asparagus racemosus). · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
14.PMID: 33689806 (2021) — Neuro-nutraceutical potential of Asparagus racemosus: A review. · Neurochemistry international
15.PMID: 36433663 (2023) — Asparagus (Asparagus racemosus L.) roots: nutritional profile, medicinal profile, preservation, and value addition. · Journal of the science of food and agriculture
16.PMID: 17240097 (2007) — Asparagus racemosus--ethnopharmacological evaluation and conservation needs. · Journal of ethnopharmacology
17.PMID: 26463825 (2016) — Asparagus racemosus: a review on its phytochemical and therapeutic potential. · Natural product research
18.PMID: 40347163 (2025) — Ashwagandha and Shatavari Extracts Dose-Dependently Reduce Menopause Symptoms, Vascular Dysfunction, and Bone Resorption in Postmenopausal Women: A Randomized, Double-Blind, Placebo-Controlled Study. · Journal of menopausal medicine