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Moderate· limited-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Black seed may interact with cyclosporine levels. Some studies suggest it may be protective, but monitoring is essential.
Thymoquinone affects multiple CYP enzymes and may alter cyclosporine metabolism.
Source: Clinical Studies · Reviewed April 2026
Black Seed + Cyclosporine: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Black seed may interact with cyclosporine levels. Some studies suggest it may be protective, but monitoring is essential.
Thymoquinone affects multiple CYP enzymes and may alter cyclosporine metabolism.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.