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Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Cassia cinnamon (high coumarin) combined with hepatotoxic medications may increase liver damage risk.
Coumarin in cassia cinnamon is hepatotoxic in susceptible individuals, creating additive risk with hepatotoxic drugs.
Source: Natural Medicines Database · Reviewed April 2026
Cinnamon + Hepatotoxic medications: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Cassia cinnamon (high coumarin) combined with hepatotoxic medications may increase liver damage risk.
Coumarin in cassia cinnamon is hepatotoxic in susceptible individuals, creating additive risk with hepatotoxic drugs.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.