This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Fenugreek may enhance blood sugar-lowering effects of sulfonylureas, increasing hypoglycemia risk.
Additive hypoglycemic effects through insulin secretion stimulation and improved insulin sensitivity.
Source: Clinical Studies · Reviewed April 2026
Fenugreek + Glipizide: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Fenugreek may enhance blood sugar-lowering effects of sulfonylureas, increasing hypoglycemia risk.
Additive hypoglycemic effects through insulin secretion stimulation and improved insulin sensitivity.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.