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Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Fenugreek contains coumarin compounds that may enhance warfarin's anticoagulant effect.
Coumarin derivatives in fenugreek may have additive anticoagulant activity.
Source: Natural Medicines Database · Reviewed April 2026
Fenugreek + Warfarin (Coumadin): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Fenugreek contains coumarin compounds that may enhance warfarin's anticoagulant effect.
Coumarin derivatives in fenugreek may have additive anticoagulant activity.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.