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Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Garlic inhibits platelet aggregation and may add to apixaban's anticoagulant effect, increasing bleeding risk. Watch for unusual bruising, nosebleeds, or blood in urine or stool.
Garlic-derived ajoene and related sulfur compounds inhibit platelet aggregation through thromboxane and ADP pathways, adding to factor Xa inhibition by apixaban.
Source: Natural Medicines Database · Reviewed September 2026
Garlic + Apixaban (Eliquis): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Garlic inhibits platelet aggregation and may add to apixaban's anticoagulant effect, increasing bleeding risk. Watch for unusual bruising, nosebleeds, or blood in urine or stool.
Garlic-derived ajoene and related sulfur compounds inhibit platelet aggregation through thromboxane and ADP pathways, adding to factor Xa inhibition by apixaban.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.