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Severe· well-documented
Avoid this combination unless your prescriber explicitly approves it with appropriate monitoring.
Garlic supplements may increase anticoagulant effect of warfarin and increase bleeding risk. Cases of increased INR and bleeding have been reported.
Garlic has antiplatelet and fibrinolytic activity that adds to warfarin's anticoagulant effect. Ajoene and allicin inhibit platelet aggregation.
Source: Natural Medicines Database · Reviewed April 2026
Garlic + Warfarin (Coumadin): high risk. Avoid this combination unless your prescriber explicitly approves it with appropriate monitoring. Garlic supplements may increase anticoagulant effect of warfarin and increase bleeding risk. Cases of increased INR and bleeding have been reported.
Garlic has antiplatelet and fibrinolytic activity that adds to warfarin's anticoagulant effect. Ajoene and allicin inhibit platelet aggregation.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.