This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Moderate· moderate-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Schisandra may increase tacrolimus blood levels through enzyme inhibition.
Schisandrin inhibits CYP3A4 and P-glycoprotein, reducing tacrolimus metabolism.
Source: Clinical Studies · Reviewed April 2026
Schisandra + Tacrolimus: use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Schisandra may increase tacrolimus blood levels through enzyme inhibition.
Schisandrin inhibits CYP3A4 and P-glycoprotein, reducing tacrolimus metabolism.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.