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AC
Not CommonRésumée par IA
Allium Cepa Herb
Allium cepa
Remède respiratoire contre les toux en médecine populaire européenne
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Allium cepa (onion) is a globally consumed vegetable with recognized nutritional and medicinal benefits [PMID:38455126], possessing a wide range of pharmacological properties including antioxidant and antimicrobial effects [PMID:30040448].
Contexte
Allium cepa L. is a member of the Amaryllidaceae family and is one of the most widely distributed species within the Allium genus [PMID:38262524, PMID:34400937]. It is cultivated worldwide across Europe, North America, Asia, and Africa [PMID:24915405].
Usages traditionnels
Onion has been used since antiquity in various indigenous cultures to manage ailments including microbial infections, respiratory, gastrointestinal, skin and cardio-vascular disorders, diabetes, renal colic, rheumatism, sexual impotence, menstrual pain, and headache [PMID:38262524].
Composés actifs
Key bioactive constituents include flavonoids (quercetin, kaempferol, and quercetin derivatives), organosulfur compounds (allicin, diallyl disulphide, diallyl trisulphide, thiosulphinates, and ALK(EN)-based cysteine sulfoxides), phenolic acids, polysaccharides, and saponins [PMID:34400937, PMID:34368207, PMID:33643564, PMID:24915405].
Mécanisme d'action
Bioactive components of Allium cepa exhibit mechanisms such as free-radical scavenging, antioxidant activity, anti-inflammatory effects, chelating agent activity, and cytoprotective activities, which help reduce lipid peroxidation and increase protein synthesis in damaged tissues [PMID:34400937].
Preuves cliniques
Preuve CDiabetes/Blood Sugar Management
Onion and its constituents are suggested to have anti-diabetic effects and the ability to manage blood sugar levels [PMID:38807798, PMID:30040448].
Preuve CCardiovascular Health
Reported benefits include antiplatelet activity, antithrombotic activity, and the ability to lower cholesterol and blood pressure [PMID:24915405, PMID:38807798].
Preuve CInflammatory and Respiratory Disorders
Suggested effectiveness in treating asthma, inflammatory disorders, and relieving coughs and colds [PMID:34567150, PMID:38807798].
Preuve CCancer
Compounds such as quercetin show promise in cancer prevention and anticancer properties [PMID:24915405, PMID:38807798].
Sécurité et effets indésirables
Handling onion can induce contact dermatitis, rhinoconjunctivitis, and asthma [PMID:30858787]. Rare cases of IgE-dependent anaphylaxis following ingestion have been reported [PMID:30858787].
Synthèse des preuves
The evidence is primarily based on reviews and preclinical (in-vitro/animal) studies (Level C and D), indicating broad pharmacological potential, though high-level clinical trial data (Level A/B) is lacking in the provided abstracts.
Sources PubMed
1.PMID: 38455126 (2024) — Onion (Allium cepa L.) and Drought: Current Situation and Perspectives. · Scientifica
2.PMID: 38262524 (2024) — An ethnopharmacological, phytochemical, and pharmacological overview of onion (Allium cepa L.). · Journal of ethnopharmacology
3.PMID: 24915405 (2015) — Onion: nature protection against physiological threats. · Critical reviews in food science and nutrition
4.PMID: 30858787 (2019) — Immunological characterization of onion (Allium cepa) allergy. · Postepy dermatologii i alergologii
5.PMID: 34400937 (2021) — Onion (Allium cepa) and its Main Constituents as Antidotes or Protective Agents against Natural or Chemical Toxicities: A Comprehensive Review.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
· Iranian journal of pharmaceutical research : IJPR
6.PMID: 34953395 (2022) — Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
7.PMID: 34567150 (2021) — Pharmacological Properties of Allium cepa, Preclinical and Clinical Evidences; A Review. · Iranian journal of pharmaceutical research : IJPR
8.PMID: 30040448 (2019) — Traditional and modern uses of onion bulb (Allium cepa L.): a systematic review. · Critical reviews in food science and nutrition
9.PMID: 38807798 (2024) — Quantification of the Anti-diabetic Effect of Allium cepa. · Cureus
10.PMID: 34368207 (2021) — Recent Advances in Bioactive Compounds, Health Functions, and Safety Concerns of Onion (Allium cepa L.). · Frontiers in nutrition
11.PMID: 33643564 (2021) — The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review. · Iranian journal of basic medical sciences