Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Alnustone reduced serum triacylglycerol, reversed liver steatosis, alleviated insulin resistance, and ameliorated fibrosis in mice [PMID: 40470949]
Ethanol extracts showed hypoglycemic effects in db/db mice; isolated diarylheptanoid-chalcone hybrids inhibited α-glucosidase and PTP1B [PMID: 33545534]
Alpinetin induced mitochondria-associated apoptosis and tumor regression in breast cancer cells [PMID: 32562470]; cardamonin showed anti-myeloma effects [PMID: 26051719]; ethanol extracts induced autophagy-related apoptosis in various cancer cells [PMID: 35730618]
Alpinetin inhibited histopathologic changes, reduced BUN and creatinine levels, and suppressed TLR4 expression and NF-κB activation in mice [PMID: 26321118]
Volatile oil (AKHO) reduced diarrhea scores and intestinal damage in mice by regulating gut microbiota and modulating the mPGES-1/PGE2/EP4 pathways [PMID: 37800952]
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 40470949 (2025) — Alnustone Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β-Oxidation via Targeting Calmodulin. · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
- 2.PMID: 35149263 (2022) — New diarylheptanoid dimers as GLP-1 secretagogues and multiple-enzyme inhibitors from Alpinia katsumadai. · Bioorganic chemistry
- 3.PMID: 41696736 (2026) — Alpinia katsumadai seed from a condiment to ethnomedicine to nutraceutical, a comprehensive review of its chemistry and health benefits. · Journal of traditional and complementary medicine
- 4.PMID: 38284732 (2024) — Alnustone: A Review of its Sources, Pharmacology, and Pharmacokinetics. · Current molecular pharmacology
- 5.PMID: 22816310