Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
A novel polysaccharide (ACSP-I) attenuated CCl4-induced liver injury in vivo and suppressed HSCs activation in vitro [PMID:41320419]; flavonoids increased SOD activity and decreased MDA content in rat models [PMID:16270385].
Ethanol extract (ACSE) improved survival rates in mouse models of acute sepsis (CLP and LPS induced) and decreased AST and ALT levels [PMID:38203555].
Flavonoids inhibited the proliferation of human hepatocarcinoma (SMMC-7721 and HepG2) and breast cancer cell lines, inducing apoptosis and reducing metastasis in nude mice [PMID:19429375, PMID:25902740].
Total flavonoid fraction induced a decrease in systolic blood pressure in renal hypertensive (RHR) and spontaneously hypertensive rats (SHR) [PMID:16201455].
70% ethanol extract of seeds suppressed elevated total cholesterol and triglycerides in rats fed a high cholesterol diet [PMID:28753987].
Synthèse des preuves
Sources PubMed
- 1.PMID: 41320419 (2026) — Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds. · Carbohydrate polymers
- 2.PMID: 41285228 (2026) — Botany, traditional uses, phytochemistry, and pharmacology of Astragali Complanati Semen (Astragalus complanatus R. Br. seeds): An updated review. · Journal of ethnopharmacology
- 3.PMID: 38203555 (2023) — Astragalus Complanatus Ethanol Attenuates Septic Shock by Exerting Anti-Inflammatory Effects on Macrophages. · International journal of molecular sciences
- 4.PMID: 24933224 (2014) — Semen Astragali Complanati: an ethnopharmacological, phytochemical and pharmacological review. · Journal of ethnopharmacology
- 5.PMID: 19429375