Chlorophytum borivilianum (Chlorophytum borivilianum): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Chlorophytum borivilianum work as an aphrodisiac?

Chlorophytum borivilianum contains steroidal saponins and stigmasterol that may influence testosterone pathways and nitric oxide production, supporting male reproductive function. The herb's adaptogenic properties are attributed to polysaccharides that may help the body manage stress, indirectly supporting sexual health. Alkaloids and vitamins contribute to its overall tonic effects. While traditionally used for thousands of years as a virility tonic, the exact mechanism remains unclear. Evidence level C indicates limited clinical research, with most support coming from traditional Ayurvedic use and preliminary studies rather than definitive mechanistic trials.

Does Chlorophytum borivilianum interact with any medications?

Chlorophytum borivilianum may interact with hormone-related medications due to its potential effects on testosterone pathways. Individuals taking hormone replacement therapy, anabolic steroids, or medications for hormone-sensitive conditions should avoid this herb. Those on diabetes or blood pressure medications should exercise caution, as adaptogenic herbs may affect these conditions. Specific drug interaction studies are lacking, so consult a healthcare provider before combining with any prescription medications, particularly those affecting hormonal balance or sexual function.

What is the recommended dosage for Chlorophytum borivilianum?

The typical adult dosage for Chlorophytum borivilianum is 500-1000mg of standardized capsule extract taken twice daily, or 3-5 grams of powdered root daily. Traditional Ayurvedic practice often divides doses throughout the day with meals to improve absorption and reduce gastrointestinal effects. Standardized products are preferred to ensure consistent saponin content. Evidence for optimal dosing is limited (Level C), based primarily on traditional use rather than clinical trials. Start with lower doses to assess tolerance before increasing.

Is Chlorophytum borivilianum safe during pregnancy?

No, Chlorophytum borivilianum is contraindicated during pregnancy and should be avoided. This herb has traditional use as a male reproductive tonic with potential hormonal effects, making it unsuitable for pregnant women. There is insufficient safety data for use during breastfeeding. Women who are pregnant, trying to conceive, or nursing should not take this supplement. The herb's effects on fetal development have not been studied, and its traditional designation as a male tonic further supports avoiding use during pregnancy.

What is Chlorophytum borivilianum used for in Ayurvedic medicine?

Chlorophytum borivilianum, known as Safed Musli, is traditionally used in Ayurvedic medicine as a premier male sexual tonic and adaptogen. Primary uses include supporting male virility, sexual function, testosterone levels, stamina, and overall vitality. It has been employed for thousands of years for sexual dysfunction and as a general rejuvenative tonic (rasayana). Modern interest focuses on its potential aphrodisiac and stress-adaptation properties. Evidence level C indicates support from traditional use and preliminary research rather than large-scale clinical trials.

What are the side effects of Chlorophytum borivilianum?

Chlorophytum borivilianum is generally well-tolerated, with most reported side effects being mild gastrointestinal symptoms such as bloating, gas, or stomach discomfort. These effects are typically dose-dependent and may be reduced by taking supplements with food. Individuals with hormone-sensitive conditions should avoid this herb due to potential effects on hormonal pathways. Long-term safety data is limited. Discontinue use if adverse reactions occur and consult a qualified healthcare provider if symptoms persist.

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Chlorophytum borivilianum, also known as Safed Musli, is a traditional Indian medicinal herb used primarily for its aphrodisiac, rejuvenating, and immunomodulatory properties [PMID:24045177, PMID:19751181].

Contexte

Chlorophytum borivilianum (Liliaceae) is an eminent medicinal plant of India, often referred to as 'white gold' or 'divya aushad' [PMID:24045177, PMID:19751181]. It is utilized across Ayurvedic, Unani, Homeopathic, and Allopathic systems of medicine [PMID:19751181].

Usages traditionnels

Traditionally used in India for treating male impotency [PMID:24045177]. It is used as a general sex tonic, aphrodisiac, and revitalizer, and to treat physical illness, weakness, diabetes, arthritis, rheumatism, joint pains, diarrhea, dysentery, gonorrhea, and leucorrhea [PMID:19751181]. It is also used to increase body immunity and address natal and postnatal problems, including increasing lactation in feeding mothers [PMID:19751181].

Composés actifs

The roots contain steroidal and triterpenoidal saponins (including Chlorophytoside-I), sapogenins, fructans, stigmasterol, and various fatty acids [PMID:19751181, PMID:21713136]. Saponins are considered the principal bioactive components [PMID:26458557].

Mécanisme d'action

The herb exhibits antioxidant activity by scavenging free radicals (DPPH and NO) and increasing the activity of endogenous enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) [PMID:37025174, PMID:25104050, PMID:20843110]. It may modulate the immune system by stimulating natural killer (NK) cell activity via its polysaccharide fraction [PMID:21792363]. In skin inflammation, it may downregulate pro-inflammatory cytokine gene expressions (IL-4, IL-6, IL-13, TNF-α) and reduce serum IgE levels [PMID:42126771].

Preuves cliniques

Preuve BSleep Quality

A dietary supplement containing C. borivilianum and velvet bean improved sleep quality across all categories of the Pittsburgh Sleep Quality Index (PSQI) in healthy men and women [PMID:22778558]

Preuve BGrowth Hormone Levels

Acute ingestion of a blend of C. borivilianum and velvet bean increased serum growth hormone in exercise-trained men, with peak values at 80 minutes post-ingestion [PMID:23946662]

Preuve DMale Reproductive Function (Animal Models)

Root extracts increased sexual vigour, libido, sperm count, and sperm motility in rats [PMID:26952773]. It prevented sperm impairment and oxidative stress in diabetic rats [PMID:25104050] and protected sperm integrity against gamma irradiation [PMID:37025174] and arsenic-induced toxicity [PMID:23534213].

Preuve DDiabetes (Animal Model)

Aqueous root extract maintained near-normal blood glucose, HbA1c, insulin, and lipid profile levels in streptozotocin-induced diabetic rats [PMID:25249786]

Preuve DHyperlipidaemia (Animal Model)

Root powder significantly increased HDL-cholesterol and decreased plasma and hepatic lipid profiles in hypercholesteraemic rats [PMID:17250646]

Sécurité et effets indésirables

Root extract showed no toxic effect up to a dose of 800 mg/kg body weight/day in animal studies [PMID:20843110]. In a human study on sleep quality, resting heart rate, blood pressure, and metabolic panels remained stable [PMID:22778558].

Grossesse et allaitement

Traditionally used to increase lactation in feeding mothers [PMID:19751181].

Synthèse des preuves

The evidence consists primarily of animal-based preclinical studies (Level D) and a few small-scale human trials (Level B) regarding sleep and growth hormone. There is strong preclinical evidence for reproductive and antioxidant benefits, but limited large-scale clinical data.

Sources PubMed

1.PMID: 24045177 (2013) — Safed musli (Chlorophytum borivilianum): a review of its botany, ethnopharmacology and phytochemistry. · Journal of ethnopharmacology
2.PMID: 26952773 (2016) — Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats. · Andrologia
3.PMID: 19751181 (2009) — Chlorophytum borivilianum: a white gold for biopharmaceuticals and neutraceuticals. · Current pharmaceutical biotechnology
4.PMID: 25104050 (2014) — Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin-induced adult male diabetic Wistar rats. · BMC complementary and alternative medicine
5.PMID: 27761075 (2016) — Induction, Subculture Cycle, and Regeneration of Callus in Safed Musli (Chlorophytum borivilianum) using Different Types of Phytohormones.

Chlorophytum borivilianum

Sources et citations

Calculer une dose sûre de Chlorophytum borivilianum

Acanthopanax Sessiliflorus

Fu Zi Hong Jing Tian

Glycyrrhiza Glabra Var Persian

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Sécurité et effets indésirables

Grossesse et allaitement

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Chlorophytum borivilianum

Sources et citations

Calculer une dose sûre de Chlorophytum borivilianum

Plantes associées

Acanthopanax Sessiliflorus

Fu Zi Hong Jing Tian

Glycyrrhiza Glabra Var Persian

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Sécurité et effets indésirables

Grossesse et allaitement

Synthèse des preuves

Sources PubMed

Sources gouvernementales