Dalea purpurea (Dalea purpurea): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Dalea purpurea work for wound healing?

Dalea purpurea contains tannins and flavonoids that contribute to its wound-healing properties. Tannins act as astringents, helping to contract tissues and form a protective barrier over wounds, while flavonoids provide anti-inflammatory and antioxidant effects that may support the healing process. The volatile oils may also contribute antimicrobial activity. These mechanisms are based on traditional use and phytochemical analysis rather than clinical trials (Evidence level C).

Does Dalea purpurea interact with any medications?

There are no well-documented drug interactions for Dalea purpurea in the scientific literature. However, the presence of tannins could potentially reduce the absorption of certain medications, including iron supplements and some alkaloid drugs, if taken simultaneously. Patients taking prescription medications should consult a qualified healthcare provider before using Dalea purpurea, as systematic interaction studies have not been conducted (Evidence level D).

What is the recommended dosage for Dalea purpurea?

The traditional adult dosage for Dalea purpurea is approximately 2 grams of dried herb prepared as a tea. This preparation is typically consumed up to three times daily for digestive complaints or used topically as a wash for wound care. Due to limited clinical research establishing optimal dosing, individuals should follow the guidance of a qualified herbalist or healthcare practitioner and avoid exceeding recommended amounts (Evidence level C).

Is Dalea purpurea safe to use during pregnancy?

Dalea purpurea is considered unsafe during pregnancy and should be avoided. Traditional knowledge and the presence of certain active compounds, including volatile oils and flavonoids, suggest potential risks to fetal development or pregnancy maintenance. Women who are pregnant, attempting to conceive, or breastfeeding should not use this herb. There is insufficient safety data to support use during these periods (Evidence level D).

What are the side effects of Dalea purpurea?

Dalea purpurea may cause mild adverse reactions in some individuals, including gastrointestinal upset, nausea, or allergic skin responses. Those with known sensitivities to plants in the Fabaceae family may be at higher risk for allergic reactions. Discontinue use if any adverse symptoms develop. Due to limited safety research, the full profile of potential side effects remains incompletely characterized (Evidence level C).

What is Dalea purpurea used for medicinally?

Dalea purpurea has been used traditionally by Native American healers for wound healing, digestive conditions, and fever treatment. The herb is applied topically to cuts, scrapes, and skin irritations, or taken internally as a tea for gastrointestinal complaints. Modern herbalists may recommend it for its anti-inflammatory properties. These uses are supported by ethnobotanical tradition rather than clinical trials (Evidence level C).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 29 articles PubMed · modèle : gemma4:31b

Résumé

Dalea purpurea, known as purple prairie clover, is a native North American legume containing bioactive condensed tannins and stilbenes [PMID:34650577, PMID:14738380].

Contexte

Dalea purpurea (purple prairie clover) is an indigenous legume found in North American prairie ecosystems [PMID:15782230, PMID:32082566]. It is used in prairie restoration and as a forage crop for livestock [PMID:15644916, PMID:32082566].

Composés actifs

The plant contains condensed tannins (CT) consisting mainly of epicatechin (EC) and epigallocatechin (EGC) subunits [PMID:34650577]. Other bioactive compounds include geranylated stilbenes such as pawhuskins A, B, and C [PMID:14738380, PMID:18922035], and the geranylated flavanone malheuran A [PMID:39861612].

Mécanisme d'action

Condensed tannins in D. purpurea exhibit protein-precipitating capacity [PMID:34650577, PMID:23396143]. They act against Escherichia coli by increasing outer membrane permeability, causing cell aggregation, and reducing growth rates [PMID:23396143, PMID:23575115]. Pawhuskin A has demonstrated affinity for the opioid receptor in vitro [PMID:14738380, PMID:18922035].

Preuves cliniques

Preuve DEscherichia coli shedding in cattle

Cattle grazing pastures containing purple prairie clover showed a linear decrease in fecal shedding of total E. coli from summer to fall [PMID:26219355].

Preuve DEscherichia coli O157:H7 (in vitro)

Condensed tannins from D. purpurea increased lag time and reduced the growth rate of E. coli O157:H7 [PMID:23575115].

Synthèse des preuves

The available evidence is primarily based on in vitro studies and animal/agricultural research (Level D), focusing on the antimicrobial properties of condensed tannins and the chemical characterization of stilbenes.

Sources PubMed

1.PMID: 34650577 (2021) — Composition and Protein Precipitation Capacity of Condensed Tannins in Purple Prairie Clover (Dalea purpurea Vent.). · Frontiers in plant science
2.PMID: 29509678 (2018) — Characterization of Condensed Tannins from Purple Prairie Clover (Dalea purpurea Vent.) Conserved as either Freeze-Dried Forage, Sun-Cured Hay or Silage. · Molecules (Basel, Switzerland)
3.PMID: 33135157 (2021) — Conserving purple prairie clover (Dalea purpurea Vent.) as hay and silage had little effect on the efficacy of condensed tannins in modulating ruminal fermentation in vitro. · Journal of the science of food and agriculture
4.PMID: 28864945 (2018) — Fecal microbiota of lambs fed purple prairie clover (Dalea purpurea Vent.) and alfalfa (Medicago sativa). · Archives of microbiology
5.PMID: 32082566 (2020)

Dalea purpurea

Sources et citations

Calculer une dose sûre de Dalea purpurea

Musa balbisiana

Velvet Tamarind

Achillea biebersteinii

Questions fréquentes

Résumé

Contexte

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Dalea purpurea

Sources et citations

Calculer une dose sûre de Dalea purpurea

Plantes associées

Musa balbisiana

Velvet Tamarind

Achillea biebersteinii

Questions fréquentes

Résumé

Contexte

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales