Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Dragon fruit (Hylocereus undatus) is a Cactaceae family fruit cultivated for its nutritional benefits and antioxidant properties [PMID:39711595, PMID:34698395].
Contexte
Also known as pitaya or pitahaya, Hylocereus undatus is an epiphytic cactus originally domesticated in Mexico and the USA, characterized by triangular-shaped stems and large flowers [PMID:39711595, PMID:36632141].
Composés actifs
The fruit contains vitamin C, betalains, and polyphenolic compounds [PMID:36014575]. Specifically, the peel of H. undatus contains flavonoids, hexadecanoic acid, linoleate, chlorogenic acid, caffeic acid, ferulic acid, rutin, and isoquercitrin [PMID:36014575, PMID:34070235].
Mécanisme d'action
Extracts from H. undatus have demonstrated the ability to inhibit cell migration and increase early apoptosis in HT-29 colon cancer cells via upregulation of Bax and caspase-12 and downregulation of Bcl-2 [PMID:42234727].
Preuves cliniques
Preuve DStress-induced impairments (C. elegans)
Microencapsulated pitaya extract was effective in preventing and/or reversing stress-induced damages to cholinergic and antioxidant systems in Caenorhabditis elegans [PMID:34698395]
Preuve DHuman colon cancer (HT-29 cells)
Peel extracts of white dragon fruit (H. undatus) showed cytotoxicity against HT-29 cells (IC50: 148.4 µg/mL) and inhibited cell migration [PMID:42234727]
Synthèse des preuves
The current evidence is primarily based on in vitro studies and animal models (C. elegans), indicating antioxidant and potential anticancer properties, but lacks human clinical trials.
Sources PubMed
- 1.PMID: 36014575 (2022) — Pitahaya Peel: A By-Product with Great Phytochemical Potential, Biological Activity, and Functional Application. · Molecules (Basel, Switzerland)
- 2.PMID: 36632141 (2023) — Stem transcriptome screen for selection in wild and cultivated pitahaya (Selenicereus undatus): an epiphytic cactus with edible fruit. · PeerJ
- 3.PMID: 39711595 (2024) — Comprehensive mapping of molecular cytogenetic markers in pitaya (Hylocereus undatus) and related species. · Frontiers in plant science
- 4.PMID: 34698395 (2022) — Fruit extract of red pitaya (Hylocereus undatus) prevents and reverses stress-induced impairments in the cholinergic and antioxidant systems of Caenorhabditis elegans. · Journal of food biochemistry
- 5.PMID: 34070235 (2021) — Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus).