Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Elderflower works primarily as a diaphoretic, meaning it induces sweating to help the body cool down and break fevers. This action is attributed to its flavonoid content, including quercetin and rutin, which may also reduce inflammation in the upper respiratory tract. By increasing peripheral blood flow and promoting perspiration, elderflower assists the body's natural temperature regulation. Evidence level: C/Traditional use supports this mechanism.
Does elderflower interact with diuretic medications?
Yes, elderflower possesses natural diuretic properties and may potentiate the effects of prescription diuretic medications (water pills). This combination could theoretically lead to dehydration or electrolyte imbalances. Patients taking lithium should also exercise caution, as increased urination may affect lithium excretion levels. While clinical trial data is limited, it is advisable to consult a healthcare provider before combining elderflower with diuretics or other medications affecting fluid balance.
What is the standard dosage for elderflower tea for colds?
The standard adult dosage for dried elderflower is 3-5 grams infused in hot water, taken three times daily. For liquid tincture extracts, the recommended dosage is 2-4 milliliters three times daily. To prepare tea, pour boiling water over the dried flowers and steep for 10-15 minutes to extract the volatile oils and flavonoids. Dosage for children should be adjusted appropriately based on weight.
Is elderflower safe to use during pregnancy?
Elderflower is generally considered safe for use during pregnancy when consumed in recommended food or therapeutic doses. Unlike elderberries, the flowers do not contain cyanogenic glycosides in significant amounts and are regarded as gentle. However, safety data is largely based on traditional use (Evidence level: C) rather than extensive clinical trials. Pregnant women should consult a qualified healthcare provider or midwife before beginning any herbal regimen.
Can elderflower help with sinus congestion and allergies?
Yes, elderflower is traditionally used to support sinus health and alleviate congestion. Its anti-inflammatory properties, derived from compounds like quercetin and chlorogenic acid, may help reduce swelling in mucous membranes. While direct clinical evidence is limited (Evidence level: C), herbalists often prescribe elderflower for allergic rhinitis and sinusitis due to its ability to dry excess mucus and reduce upper respiratory inflammation.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 18 articles PubMed · modèle : gemma4:31b
Résumé
Black elderflower (Sambucus nigra) is traditionally used to treat colds, flu, and inflammatory conditions [PMID: 36559324, 34443417, 9324006].
Contexte
Sambucus nigra flowers are a plant tissue rich in polyphenolic phytochemicals used in various pharmaceutical forms, including teas, syrups, and extracts [PMID: 36559324, 32093048, 27162290].
Usages traditionnels
Traditionally used for the relief of early symptoms of the common cold [PMID: 34443417], treatment of colds and flu [PMID: 36559324], and in Turkish folk medicine for inflammatory diseases such as rheumatism, fever, infections, and edemas [PMID: 9324006]. In Poland, it has been used in syrups for feverishness accompanying upper respiratory tract infections in children [PMID: 27162290].
Composés actifs
The chemical composition mainly consists of polyphenolic compounds, including flavonoids (specifically quercetin 3-rutinoside [PMID: 34356325]), hydroxycinnamic acids, and triterpenes [PMID: 34443417]. Other identified components include lignans [PMID: 27740591], narcissoside [PMID: 36358461], and kynurenic acid [PMID: 24364456].
Mécanisme d'action
Elderflower extracts exhibit antioxidant properties by neutralizing reactive oxygen species (ROS) [PMID: 36559324, 34443417]. Narcissoside may enhance the MiR200a/Nrf-2/GSH axis and mediate MAPK/Akt signaling pathways to resist apoptosis [PMID: 36358461]. Aqueous extracts can induce ATP binding cassette transporter A1 (ABCA1) expression to reduce cholesteryl ester accumulation in foam cells [PMID: 38347122]. Additionally, it has been shown to inhibit proinflammatory activities of periodontal pathogens and inhibit the biosynthesis of inflammatory cytokines such as IL-1alpha, IL-1beta, and TNF-alpha [PMID: 16460254, 9324006].
Preuves cliniques
Preuve DUpper Respiratory Tract Infections/Fever
Used in pharmaceutical syrups for children to treat feverishness accompanying upper respiratory tract infections [PMID: 27162290].
Preuve DPeriodontitis/Inflammation
Aqueous extracts potently inhibit proinflammatory activities of major virulence factors from Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in vitro [PMID: 16460254].
Preuve DAtherosclerosis (Foam Cell Formation)
Aqueous elder extracts induce ABCA1 expression and reduce cholesteryl ester accumulation in aggregated LDL-induced foam cells [PMID: 38347122].
Preuve DNeurodegeneration (Parkinson's Model)
Narcissoside from elderflowers reduced ROS generation and degeneration of dopaminergic neurons in C. elegans and SH-SY5Y cells [PMID: 36358461].
Sécurité et effets indésirables
Flowers from urban areas were found to contain metals (K, Ca, Cu, Rb, Fe, Cr, Zn) at levels below those harmful to humans [PMID: 31808083].
Synthèse des preuves
The current evidence is primarily based on in vitro cell cultures, animal models (C. elegans), and traditional use reports; there are no high-level clinical trials (RCTs) or meta-analyses provided in the source set.
Sources PubMed
1.PMID: 36559324 (2022) — Comparison of the Formulation, Stability and Biological Effects of Hydrophilic Extracts from Black Elder Flowers (Sambucus nigra L.). · Pharmaceutics
4.PMID: 34443417 (2021) — Biological Actions and Molecular Mechanisms of Sambucus nigra L. in Neurodegeneration: A Cell Culture Approach. · Molecules (Basel, Switzerland)
5.PMID: 34356325 (2021) — The Physicochemical and Antioxidant Properties of Sambucus nigra L. and Sambucus nigra Haschberg during Growth Phases: From Buds to Ripening.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 31808083 (2020) — Selected metal content and antioxidant capacity of Sambucus nigra flowers from the urban areas versus soil parameters and traffic intensity. · Environmental science and pollution research international
7.PMID: 32093048 (2020) — A Green Extraction Process for Polyphenols from Elderberry (Sambucus nigra) Flowers Using Deep Eutectic Solvent and Ultrasound-Assisted Pretreatment. · Molecules (Basel, Switzerland)
8.PMID: 10888553 (2000) — Olfactory and quantitative analysis of aroma compounds in elder flower (Sambucus nigra L.) drink processed from five cultivars. · Journal of agricultural and food chemistry
9.PMID: 16460254 (2006) — Inhibition of proinflammatory activities of major periodontal pathogens by aqueous extracts from elder flower (Sambucus nigra). · Journal of periodontology
10.PMID: 24364456 (2013) — Kynurenic acid content in anti-rheumatic herbs. · Annals of agricultural and environmental medicine : AAEM
11.PMID: 35337239 (2022) — Water soluble microparticles of Sambucus nigra L. (elderberry) as a potential herbal medicine. · Natural product research
12.PMID: 36358461 (2022) — Neuroprotective Capability of Narcissoside in 6-OHDA-Exposed Parkinson's Disease Models through Enhancing the MiR200a/Nrf-2/GSH Axis and Mediating MAPK/Akt Associated Signaling Pathway. · Antioxidants (Basel, Switzerland)
13.PMID: 9324006 (1997) — Inhibitory effects of Turkish folk remedies on inflammatory cytokines: interleukin-1alpha, interleukin-1beta and tumor necrosis factor alpha. · Journal of ethnopharmacology
14.PMID: 27740591 (2016) — Effects of Phytoestrogen Extracts Isolated from Elder Flower on Hormone Production and Receptor Expression of Trophoblast Tumor Cells JEG-3 and BeWo, as well as MCF7 Breast Cancer Cells. · Nutrients
15.PMID: 22112724 (2011) — Antiviral activity in vitro of two preparations of the herbal medicinal product Sinupret® against viruses causing respiratory infections. · Phytomedicine : international journal of phytotherapy and phytopharmacology
16.PMID: 1639901 (1992) — Separation of flavonol-2-O-glycosides from Calendula officinalis and Sambucus nigra by high-performance liquid and micellar electrokinetic capillary chromatography. · Journal of chromatography