Ji Xue Teng (Spatholobus suberectus): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Ji Xue Teng work to improve blood circulation?

Ji Xue Teng contains bioactive isoflavones including formononetin, ononin, prunetin, and calycosin, which are believed to promote blood circulation and reduce blood stasis. These compounds may help dilate blood vessels and improve microcirculation. In Traditional Chinese Medicine theory, the herb nourishes and invigorates blood while relaxing sinews and tendons. Research on its specific mechanisms remains limited (Evidence Level C), with most understanding derived from traditional use and preliminary pharmacological studies rather than robust clinical trials.

Can Ji Xue Teng be taken with blood thinners or anticoagulants?

Ji Xue Teng should not be combined with anticoagulant or antiplatelet medications. The herb's blood-invigorating properties may enhance the effects of blood thinners such as warfarin, aspirin, clopidogrel, or heparin, potentially increasing bleeding risk. This interaction is well-documented in TCM contraindications. Patients taking anticoagulants should avoid Ji Xue Teng entirely. Always consult a qualified healthcare provider before combining herbal medicines with prescription anticoagulants, as serious bleeding complications can occur.

What is the standard dosage for Ji Xue Teng?

The typical adult dosage for Ji Xue Teng is 9–15 grams as a decoction (boiled in water) or approximately 400mg as a standardized extract, taken daily. Dosage may vary based on the specific formulation, condition being treated, and individual factors. Traditional Chinese Medicine practitioners often adjust doses based on pulse and tongue diagnosis. This herb should only be used under guidance from a qualified TCM practitioner or healthcare provider familiar with its properties and appropriate dosing.

Is Ji Xue Teng safe to take during pregnancy?

Ji Xue Teng is contraindicated during pregnancy and should be avoided. The herb's blood-invigorating and blood-moving properties can stimulate uterine contractions and increase menstrual flow, which may pose risks of miscarriage or pregnancy complications. TCM practitioners strictly prohibit its use in pregnant patients. Women who are pregnant, trying to conceive, or breastfeeding should not use this herb. Always inform your healthcare provider of all herbal supplements if you are pregnant or planning pregnancy.

What conditions is Ji Xue Teng used to treat?

Ji Xue Teng is primarily used in Traditional Chinese Medicine to address blood deficiency and blood stasis patterns. Common indications include menstrual disorders such as irregular periods, amenorrhea, and dysmenorrhea, as well as rheumatic conditions, numbness, and weakness in the limbs. The herb is valued for its dual action of nourishing blood while invigorating circulation. Evidence supporting these uses is limited (Evidence Level C), based primarily on traditional use and preliminary research rather than large-scale clinical trials.

What are the side effects of Ji Xue Teng?

Ji Xue Teng is generally well-tolerated when used appropriately, but some individuals may experience side effects. The most commonly reported adverse effects include mild nausea and increased menstrual flow. Because the herb promotes blood circulation, it may cause heavier than normal menstrual bleeding in some women. Individuals with bleeding disorders should avoid this herb entirely. Side effects are more likely at higher doses or with prolonged use. Discontinue use and consult a healthcare provider if adverse reactions occur.

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Spatholobus suberectus (Ji Xue Teng) is a leguminous medicinal plant used in traditional medicine for its blood-activating, anti-inflammatory, and antioxidant properties [PMID:36139460, 37062528].

Contexte

Spatholobus suberectus Dunn is a medicinal plant belonging to the Leguminosae family, primarily distributed in China and some Southeast Asian countries [PMID:31273216, 37062528]. The dried lianoid vine stem is the primary part used for medicinal purposes [PMID:37062528, 36222556].

Usages traditionnels

It has been used in traditional Chinese medicine for hundreds of years to promote blood circulation, tonify blood, regulate menstruation, relieve pain, and treat rheumatic arthralgia, numbness, paralysis, and blood deficiency [PMID:37062528, 38462913].

Composés actifs

The plant is rich in flavonoids, including catechin, genistein, naringenin, formononetin, isoliquiritigenin, and medicarpin [PMID:31890055, 40329176]. Other isolated compounds include protocatechuic acid, liquiritigenin, and various pterocarpans [PMID:23302527, 15283457].

Mécanisme d'action

Mechanisms include the activation of AMPK-ACC and K-Ras-ERK signaling pathways to inhibit lipogenesis in breast cancer [PMID:38020549], inhibition of the glycoprotein IIb/IIIa receptor to exert antiplatelet effects [PMID:21211555], and suppression of proinflammatory chemokine production via inhibition of MAPK phosphorylation and NF-κB pathways [PMID:35795574, 40872712]. It also demonstrates neuroprotection by modulating oxidative stress markers and cytokines [PMID:27725876].

Preuves cliniques

Preuve DAtopic Dermatitis

Water extract alleviated AD-like symptoms, including ear thickness and epidermal thickness, and suppressed proinflammatory chemokines in mice [PMID:35795574]

Preuve DTriple-Negative Breast Cancer

Extract inhibited lipogenesis and tumorigenesis while promoting fatty acid oxidation in vitro and in vivo [PMID:38020549]

Preuve DViral Entry (SARS-CoV-2, SARS-CoV-1, H5N1)

Percolation extract acted as a broad-spectrum viral entry inhibitor by blocking the SARS-CoV-2 spike glycoprotein and host ACE2 receptor [PMID:35943221]

Preuve DCerebral Ischemia

Treatment significantly provided neuroprotective effects in rat models by reducing oxidative stress and DNA damage [PMID:27725876]

Preuve DPlatelet Aggregation

Ethanol extract significantly inhibited ADP- and collagen-induced platelet aggregation in human plasma [PMID:21211555]

Preuve DGlucocorticoid-Induced Osteoporosis

Synthèse des preuves

The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating significant pharmacological potential in anti-inflammatory, anti-cancer, antiviral, and bone-protective activities.

Sources PubMed

1.PMID: 37895122 (2023) — Plant Extracts as Skin Care and Therapeutic Agents. · International journal of molecular sciences
2.PMID: 36139460 (2022) — A Review of the Pharmacological Potential of Spatholobus suberectus Dunn on Cancer. · Cells
3.PMID: 31273216 (2019) — A draft genome for Spatholobus suberectus. · Scientific data
4.PMID: 38515727 (2024) — Shade responses and resistant mechanisms in Spatholobus suberectus. · Heliyon
5.PMID: 23302527 (2012) — Chemical constituents of Spatholobus suberectus. · Chinese journal of natural medicines
6.PMID: 33013959

Ji Xue Teng

Sources et citations

Calculer une dose sûre de Ji Xue Teng

Saussurea Obvallata

Dok Khem

Curcuma phaeocaulis

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Ji Xue Teng

Sources et citations

Calculer une dose sûre de Ji Xue Teng

Plantes associées

Saussurea Obvallata

Dok Khem

Curcuma phaeocaulis

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales