Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Composés actifs
Mécanisme d'action
Preuves cliniques
Significantly reduced systolic blood pressure, diastolic blood pressure, fasting blood sugar, and hemoglobin A1c [PMID:39987124].
Significantly improved legs' heaviness and subcutaneous edema, and reduced venous pressure [PMID:11081989].
Significantly reduced salivary MMP-8 levels and serum IL-6 levels following non-surgical periodontal therapy [PMID:40362854].
Reduced smoke-induced platelet aggregation in cigarette smokers to the level of nonsmokers [PMID:10882879].
Provides photoprotection, may reduce hyperpigmentation, and improve skin barrier function and extracellular matrix homeostasis [PMID:26492562].
Studied as part of a supplement combination (with Boswellia, MSM, and curcumin) to investigate efficacy on hand pain [PMID:33617972].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 38757130 (2024) — Pycnogenol® French maritime pine bark extract in randomized, double-blind, placebo-controlled human clinical studies. · Frontiers in nutrition
- 2.PMID: 38757126 (2024) — Review of the pharmacokinetics of French maritime pine bark extract (Pycnogenol®) in humans. · Frontiers in nutrition
- 3.PMID: 33617972 (2021) — Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study. · Osteoarthritis and cartilage
- 4.PMID: 39987124 (2025) — Does supplementation with pine bark extract improve cardiometabolic risk factors? A systematic review and meta-analysis. · BMC complementary medicine and therapies
- 5.PMID: 22049273