Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Sideritis scardica exerts its effects primarily through flavonoids like hypolaetin and isoscutellarein, along with phenolic acids such as caffeic acid. These compounds demonstrate significant antioxidant activity by scavenging free radicals and reducing oxidative stress. Research suggests these constituents inhibit pro-inflammatory pathways, specifically suppressing cytokine production, which explains its traditional use for respiratory inflammation and digestive support (Evidence Level C).
Does Sideritis tea interact with medications?
Currently, there are no well-documented severe drug interactions associated with Sideritis scardica. Because the herb possesses mild anti-inflammatory properties, it may theoretically potentiate the effects of anticoagulant or antiplatelet medications, though clinical evidence is lacking (Evidence Level D). Patients taking prescription blood thinners or other medications should consult a healthcare provider before adding herbal supplements to their regimen.
What is the recommended dosage for Sideritis scardica?
The standard adult dosage for Sideritis scardica involves steeping 3 to 5 grams of dried herb in boiling water for at least 10 minutes. This preparation is typically consumed as a tea one to three times daily. This dosage aligns with traditional usage patterns for respiratory and digestive support. Due to limited clinical trial data standardizing therapeutic doses, users should adhere to amounts commonly found in traditional tea preparations (Evidence Level C).
Is Sideritis scardica safe during pregnancy?
Sideritis scardica is generally considered safe for consumption during pregnancy when used in moderate amounts as a beverage. Traditional use in the Balkans suggests no adverse outcomes, and it is often consumed as a daily tonic. However, pregnant women should avoid excessive consumption of medicinal doses and consult their midwife or doctor before using herbal remedies to ensure it fits their specific health profile (Evidence Level D/Traditional).
What are the benefits of drinking Sideritis tea?
Sideritis tea is traditionally used to support respiratory health, aiding in the relief of colds, flu, and bronchitis. Its benefits are attributed to anti-inflammatory and antimicrobial properties derived from compounds like sideridiol. It also serves as a digestive tonic, helping to soothe gastrointestinal discomfort. Furthermore, the herb provides antioxidant support, protecting cells from oxidative damage (Evidence Level C).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Sideritis scardica, commonly known as Greek mountain tea, is a Balkan endemic plant recognized for its antioxidant, anti-inflammatory, and neuroprotective properties [PMID:32824863, 38068562].
Contexte
Sideritis scardica (Lamiaceae family) is an endemic species from the mountainous regions of the Balkan Peninsula [PMID:38202787, 24487281]. It is also referred to as 'mountain tea' or 'Olympus tea' [PMID:38202787].
Usages traditionnels
Traditionally consumed as a tea in the Balkans to strengthen the body, improve mood, and treat respiratory issues such as bronchitis, bronchial asthma, common cold, and lung emphysema [PMID:32824863, 24487281]. It is also used for gastrointestinal disorders, inflammation, coughs, and as a supplement to prevent anemia [PMID:24487281, 37655384].
Composés actifs
The plant contains a diverse range of metabolites, including polyphenols, flavonoids, hydroxy-cinnamic acids [PMID:30042362], terpenoids, and phenolics [PMID:38339117]. Specific analysis identified over 100 metabolites, including carboxylic and hydroxybenzoic acids, acylquinic acids, phenylpropanoid glycosides, iridoid glycosides, and fatty acids [PMID:38202787]. It also contains a pectic polysaccharide fraction rich in uronic acids [PMID:33712146].
Mécanisme d'action
Sideritis scardica exhibits antioxidant and anti-inflammatory effects [PMID:32824863]. It acts as a triple monoamine reuptake inhibitor, preventing the reuptake of serotonin, noradrenaline, and dopamine [PMID:22622367, 36872784]. It may also increase cerebral blood flow (CBF) [PMID:30042362] and inhibit acetylcholinesterase (AChE) [PMID:36872784, 37761205].
Preuves cliniques
Preuve BCognition and Mood
A double-blind, randomized, placebo-controlled trial in older adults assessed cognitive and mood outcomes, as well as cerebral blood flow, following administration of 475 and 950 mg doses [PMID:30042362].
Preuve DCognitive Impairment (Animal Models)
Extracts mitigated scopolamine-induced learning and memory impairment in mice [PMID:36872784] and rats [PMID:38339117].
Preuve DAlzheimer's Disease (Cell/Model)
Extracts demonstrated neuroprotective activity against Aβ25-35 toxicity [PMID:37111938] and inhibited aggregation and toxicity of amyloid-β in C. elegans [PMID:29736334].
Sécurité et effets indésirables
In a 28-day repeated-dose toxicity study in rats, the no-observed-adverse-effect-level (NOAEL) for a 20% ethanol extract was determined to be 1000 mg/kg bw, with no mortality or gross pathological abnormalities detected [PMID:29937516].
Interactions médicamenteuses
A study on healthy subjects found that S. scardica decoction reduced the CYP1A2 index by approximately 16% in saliva and 8% in urine [PMID:30266316].
Synthèse des preuves
Evidence consists primarily of in vitro studies, animal models (D), and one human randomized controlled trial (B). While neuroprotective and antioxidant effects are well-documented in lab settings, human clinical data is limited.
Sources PubMed
1.PMID: 32824863 (2020) — Polyphenols and Other Bioactive Compounds of Sideritis Plants and Their Potential Biological Activity. · Molecules (Basel, Switzerland)
2.PMID: 36872784 (2023) — Effects of Sideritis scardica Extract on Scopolamine-Induced Learning and Memory Impairment in Mice. · Journal of Alzheimer's disease : JAD
3.PMID: 38202787 (2023) — A Comprehensive Phytochemical Analysis of Sideritis scardica Infusion Using Orbitrap UHPLC-HRMS. · Molecules (Basel, Switzerland)
4.PMID: 37655384 (2023) — Subchronic toxicity of Sideritis scardica, Lamiaceae on male Wistar rats. · Folia medica
5.PMID: 30042362 (2018) — The Acute and Chronic Cognitive and Cerebral Blood Flow Effects of a Sideritis scardica (Greek Mountain Tea) Extract: A Double Blind, Randomized, Placebo Controlled, Parallel Groups Study in Healthy Humans.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 24487281 (2014) — Sideritis scardica Griseb., an endemic species of Balkan peninsula: traditional uses, cultivation, chemical composition, biological activity. · Journal of ethnopharmacology
7.PMID: 38068562 (2023) — Antioxidant and Antitumor Potential of Micropropagated Balkan Endemic Sideritis scardica Griseb. · Plants (Basel, Switzerland)
8.PMID: 33712146 (2021) — Structural study of a pectic polysaccharide fraction isolated from "mountain tea" (Sideritis scardica Griseb.). · Carbohydrate polymers
9.PMID: 38339117 (2024) — Extracts of Sideritis scardica and Clinopodium vulgare Alleviate Cognitive Impairments in Scopolamine-Induced Rat Dementia. · International journal of molecular sciences
11.PMID: 30266316 (2018) — Dietary effects of Sideritis scardica "mountain tea" on human in vivo activities of xenobiotic metabolizing enzymes in healthy subjects. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
12.PMID: 37241947 (2023) — Comparative Study on Assisted Solvent Extraction Techniques for the Extraction of Biologically Active Compounds from Sideritis raeseri and Sideritis scardica. · Molecules (Basel, Switzerland)
13.PMID: 37761205 (2023) — Kombucha Fermentation of Olympus Mountain Tea (Sideritis scardica) Sweetened with Thyme Honey: Physicochemical Analysis and Evaluation of Functional Properties. · Foods (Basel, Switzerland)
14.PMID: 34655064 (2021) — HPTLC Fingerprint Authentication of Selected Sideritis spp. Using a Pharmacognostic Approach. · Planta medica
15.PMID: 37375165 (2023) — Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia. · Molecules (Basel, Switzerland)
16.PMID: 30428206 (2017) — Effects of Gamma-Irradiation on the Antioxidant Potential of Traditional Bulgarian Teas. · Natural product communications
17.PMID: 29937516 (2018) — Assessment of the Acute and Subchronic Toxicity and Mutagenicity of Sideritis scardica Griseb. Extracts. · Toxins
18.PMID: 37447102 (2023) — Plant Growth Regulators and Activated Charcoal Selectively Affect Phenylethanoid and Flavone Glycoside Accumulation in Sideritis scardica Griseb. Tissue Culture. · Plants (Basel, Switzerland)
19.PMID: 36746369 (2023) — Sideritis L. essential oils: A systematic review. · Phytochemistry
20.PMID: 22622367 (2012) — Extracts of Sideritis scardica as triple monoamine reuptake inhibitors. · Journal of neural transmission (Vienna, Austria : 1996)
21.PMID: 29736334 (2018) — Sideritis scardica extracts inhibit aggregation and toxicity of amyloid-β in Caenorhabditis elegans used as a model for Alzheimer's disease. · PeerJ
22.PMID: 25918814 (2014) — Aroma compounds of mountain tea (Sideritis scardica and S. raeseri) from western Balkan. · Natural product communications
23.PMID: 38338989 (2024) — An Innovative Approach to a Potential Neuroprotective Sideritis scardica-Clinoptilolite Phyto-Nanocarrier: In Vitro Investigation and Evaluation. · International journal of molecular sciences
24.PMID: 29914017 (2018) — Beneficial Effects of Sideritis scardica and Cichorium spinosum against Amyloidogenic Pathway and Tau Misprocessing in Alzheimer's Disease Neuronal Cell Culture Models. · Journal of Alzheimer's disease : JAD
25.PMID: 17654287 (2007) — Chemical constituents of the essential oils of Sideritis scardica Griseb. and Sideritis raeseri Boiss and Heldr. from Bulgaria and Macedonia. · Natural product research
26.PMID: 32116669 (2019) — Phenolic Profile and Bioactivities of Sideritis perfoliata L.: The Plant, Its Most Active Extract, and Its Broad Biological Properties. · Frontiers in pharmacology
27.PMID: 23649594 (2013) — Bioactive-rich Sideritis scardica tea (mountain tea) is as potent as Camellia sinensis tea at inducing cellular antioxidant defences and preventing oxidative stress. · Journal of the science of food and agriculture
28.PMID: 37509192 (2023) — Chemical Composition of the Essential Oils of Three Popular Sideritis Species Cultivated in Greece Using GC-MS Analysis. · Biomolecules
29.PMID: 36015136 (2022) — Phytochemical Composition and Cytoprotective Properties of the Endemic Sideritis sipylea Boiss Greek Species: A Valorization Study. · Pharmaceuticals (Basel, Switzerland)
30.PMID: 40311621 (2025) — Satellite-observed mountain greening predicts genomic erosion in a grassland medicinal herb over half a century. · Current biology : CB