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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 28 articles PubMed · modèle : gemma4:31b
Résumé
Spirulina (Arthrospira platensis) is an edible cyanobacterium rich in proteins, vitamins, and bioactive compounds with potential antioxidant and anti-inflammatory therapeutic benefits [PMID:30000909, PMID:36080350].
Contexte
Spirulina is a multicellular, filamentous, prokaryotic blue-green alga (cyanobacterium) [PMID:36080350]. It is classified into three genera: Spirulina, Arthrospira, and Limnospira [PMID:39272527].
Usages traditionnels
It has been applied for over 400 years [PMID:36453480] and has been utilized as a food source since ancient times [PMID:38892686].
Composés actifs
Key compounds include proteins, B vitamins, vitamin E, chlorophyll, beta-carotene, iron [PMID:30000909], omega-3 and omega-6 fatty acids [PMID:36080350], phenols, phycocyanin pigment (specifically C-phycocyanin), and polysaccharides [PMID:36080350, PMID:35946342]. It also contains inositolphosphoceramides [PMID:32297342].
Mécanisme d'action
Spirulina exhibits antioxidant and anti-inflammatory activities [PMID:36080350]. The chromophore phycocyanobilin (PCB) acts as a potent inhibitor of NADPH oxidase activity [PMID:18158824], which may decrease interleukin 6 and lower insulin resistance [PMID:38251049].
A triple-blind, placebo-controlled trial investigated the impact of 1g/day spirulina on inflammatory biomarkers and quality of life [PMID:40877830].
Preuve CCardiometabolic risk factors
Effective in reducing body weight, BMI, waist circumference, triglycerides, and LDL cholesterol, while increasing HDL cholesterol and reducing fasting blood sugar [PMID:38251049].
Preuve CArsenic toxicity
Five clinical studies reported protective effects against arsenic toxicity in humans [PMID:32749124].
Preuve CGeneral Pharmacological Effects
Attributed functions include antioxidative, anti-inflammatory, anti-neoplastic, hypolipidemic, antiviral, immunomodulatory, antimicrobial, anti-atherogenic, anti-diabetic, and radio-protective effects [PMID:36453480].
Sécurité et effets indésirables
Generally well tolerated under controlled conditions [PMID:30000909]. Minor adverse effects include diarrhea, bloating, upset stomach, flatulence, edema, headache, muscle pain, facial flushing, and sweating [PMID:30000909]. Hypersensitivity/allergies have been reported in case studies [PMID:38611357, PMID:35842084]. Products grown in uncontrolled conditions may contain heavy metals or be contaminated with Microcystis aeruginosa, which produces hepatotoxins called microcystins [PMID:30000909].
Grossesse et allaitement
No specific lactation-related uses; no data exist on safety/efficacy in nursing mothers or infants, though breastmilk discoloration (green) has been reported in one case [PMID:30000909].
Synthèse des preuves
The evidence consists primarily of reviews and preclinical/animal studies (Level C and D), with limited randomized controlled trials (Level B) for specific conditions like RRMS.
Sources PubMed
1.PMID: 30000909 (2006) — Spirulina- An Edible Cyanobacterium with Potential Therapeutic Health Benefits and Toxicological Consequences. · Journal of the American Nutrition Association
2.PMID: 36080350 (2022) — Trends and Technological Advancements in the Possible Food Applications of Spirulina and Their Health Benefits: A Review. · Molecules (Basel, Switzerland)
3.PMID: 32133854 (2020) — The True Value of Spirulina. · Journal of agricultural and food chemistry
4.PMID: 38611357 (2024) — Spirulina (Arthrospira platensis): Antiallergic Agent or Hidden Allergen? A Literature Review. · Foods (Basel, Switzerland)
5.PMID: 39272527 (2024) — Spirulina/Arthrospira/Limnospira-Three Names of the Single Organism.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 35946342 (2022) — Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes. · Bioengineered
7.PMID: 37270039 (2023) — Cultivation of blue green algae (Arthrospira platensis Gomont, 1892) in wastewater for biodiesel production. · Chemosphere
8.PMID: 39768246 (2024) — Spirulina (Arthrospira platensis) Used as Functional Feed Supplement or Alternative Protein Source: A Review of the Effects of Different Dietary Inclusion Levels on Production Performance, Health Status, and Meat Quality of Broiler Chickens. · Life (Basel, Switzerland)
9.PMID: 36453480 (2023) — An Overview of Pharmacological and Clinical Aspects of Spirulina. · Current drug discovery technologies
10.PMID: 33926055 (2021) — Blue-Green Algae (Spirulina platensis) Alleviates the Negative Impact of Heat Stress on Broiler Production Performance and Redox Status. · Animals : an open access journal from MDPI
11.PMID: 38892686 (2024) — Nutraceutical Features of the Phycobiliprotein C-Phycocyanin: Evidence from Arthrospira platensis (Spirulina). · Nutrients
12.PMID: 35842084 (2022) — Delayed IgE-mediated hypersensitivity to Arthrospira platensis (spirulina). · Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
13.PMID: 38544605 (2024) — A Study on the Brewing of "Prot-Tea" by Blending Spirulina (Arthrospira platensis) With Green Tea. · Cureus
14.PMID: 40877830 (2025) — Effects of spirulina (Arthrospira) platensis supplementation on inflammation, physical and mental quality of life, and anthropometric measures in patients with relapsing-remitting multiple sclerosis (RRMS): a triple-blinded, randomized, placebo-controlled trial. · Nutrition journal
15.PMID: 36502311 (2023) — Effects of Arthrospira platensis-derived phycocyanin on blood cells1. · Clinical hemorheology and microcirculation
16.PMID: 18158824 (2007) — Clinical potential of Spirulina as a source of phycocyanobilin. · Journal of medicinal food
17.PMID: 32297342 (2020) — The occurrence of inositolphosphoceramides in spirulina microalgae. · Electrophoresis
18.PMID: 33612469 (2020) — Spirulina platensis (Blue-green algae): A miracle from sea combats the oxidative stress and improves behavioral deficits in an animal model of Schizophrenia. · Pakistan journal of pharmaceutical sciences
19.PMID: 41465729 (2025) — Arthrospira platensis as Protein-Rich Source for Human Nutrition. · Life (Basel, Switzerland)
20.PMID: 2114613 (1990) — The nutritional value of dehydrated, blue-green algae (Spirulina platensis) for poultry. · Poultry science
21.PMID: 32749124 (2020) — The Role of Spirulina (Arthrospira) in the Mitigation of Heavy-Metal Toxicity: An Appraisal. · Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer
22.PMID: 38791586 (2024) — Antimicrobial Activity of Arthrospira (Former Spirulina) and Dunaliella Related to Recognized Antimicrobial Bioactive Compounds. · International journal of molecular sciences
23.PMID: 35811624 (2022) — Physicochemical degradation of phycocyanin and means to improve its stability: A short review. · Journal of pharmaceutical analysis
24.PMID: 34699561 (2021) — The value of blue-green algae (Spirulina platensis) as a nutritive supplement and toxicant against almond moth [Cadra cautella (Lepidoptera: Pyralidae)]. · PloS one
25.PMID: 38002153 (2023) — Use of Cyanobacterium Spirulina (Arthrospira platensis) in Buffalo Feeding: Effect on Mozzarella Cheese Quality. · Foods (Basel, Switzerland)
26.PMID: 36294932 (2022) — Lipophilic and Hydrophilic Compounds from Arthrospira platensis and Its Effects on Tissue and Blood Cells-An Overview. · Life (Basel, Switzerland)
27.PMID: 38251049 (2024) — The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review. · Journal of dietary supplements