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Harpagophytum procumbens
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
This herb may interact with medications you are taking. Review the interactions table below and consult your healthcare provider before use.
Devil's claw is native to southern Africa and has been used by indigenous San and Khoi peoples for centuries for pain and digestive complaints. It gained popularity in Europe in the 1950s and is now one of the most commonly used herbal analgesics. Its name refers to the fruit's hooked thorns.
Devil's claw is native to southern Africa and has been used by indigenous San and Khoi peoples for centuries for pain and digestive complaints. It gained popularity in Europe in the 1950s and is now one of the most commonly used herbal analgesics. Its name refers to the fruit's hooked thorns. Key active compounds include Harpagoside, Harpagide, Procumbide.
Harpagoside, along with Harpagide and Procumbide, are the primary bioactive compounds in Devil's Claw. These compounds stimulates digestive enzyme secretion and GI motility, acts on pain pathways via anti-inflammatory and neuroactive effects.
Osteoarthritis
Supported by clinical evidence; more large-scale trials would strengthen findings
Low back pain
Supported by clinical evidence; more large-scale trials would strengthen findings
Rheumatic pain
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Loss of appetite
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Digestive complaints
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Pain relief
Based on traditional use; clinical evidence limited
Fever reduction
Based on traditional use; clinical evidence limited
Digestive aid
Based on traditional use; clinical evidence limited
| Drug | Severity | Description |
|---|---|---|
| Warfarin (Coumadin) | Moderate | Devil's claw may affect blood clotting and interact with warfarin therapy. |
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