PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanol extract (50 mg/kg/day for 14 days in rats) effectively suppressed disturbed heart response to perfusion pressure changes and reduced prooxidants [PMID:37372007]
Methanol extract (500 mg/kg for 28 days in hypertensive rats) preserved cardiac contractility, systolic and diastolic function, and reduced structural damage [PMID:30632812, 30863479]
An oral liquid formulation of ethanol extract effectively reduced blood pressure in spontaneously hypertensive rats [PMID:39125920]
A mucoadhesive oral gel based on ethanol extract significantly decreased ulcer size in rats [PMID:35897855]
Extract administration (125 mg/kg for 4 weeks in rats) mitigated cardiovascular events and showed therapeutic potential in imiquimod-induced models [PMID:39894905, 40806422]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37372007 (2023) — Lady's Bedstraw as a Powerful Antioxidant for Attenuation of Doxorubicin-Induced Cardiotoxicity. · Antioxidants (Basel, Switzerland)
- 2.PMID: 40333892 (2025) — A Review of Phytochemical and Pharmacological Studies on Galium verum L., Rubiaceae. · Molecules (Basel, Switzerland)
- 3.PMID: 39125920 (2024) — Hypotensive and Cardioprotective Potential of Yellow Bedstraw Extract-Based Oral Liquid in Spontaneously Hypertensive Rats. · International journal of molecular sciences
- 4.PMID: 36985838 (2023) — Phytochemical Screening and Antioxidant Activity of Selected Estonian Galium Species. · Molecules (Basel, Switzerland)
- 5.PMID: 18636371 (2008)