PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Oral administration of T. repens leaf extract in mice led to the normalization of kidney weight, renal profile biochemistry, serum electrolytes, reduced glutathione, and lipid peroxidation [PMID:33240744].
T. repens and its isoflavonoid-rich fraction showed high cytotoxic effects in K562 cells with IC50 values of 1.67 and 0.092 mg/mL, respectively [PMID:32041350].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 3149931 (1988) — The molecular biology of cyanogenesis. · Ciba Foundation symposium
- 2.PMID: 1368366 (1992) — Saponins from Trifolium repens. · Phytochemistry
- 3.PMID: 37312068 (2023) — High-quality chromosome-level de novo assembly of the Trifolium repens. · BMC genomics
- 4.PMID: 37542471 (2023) — Haplotype-Resolved, Chromosome-Level Assembly of White Clover (Trifolium repens L., Fabaceae). · Genome biology and evolution
- 5.PMID: 34320221 (2021) — Dual-species origin of an adaptive chemical defense polymorphism. · The New phytologist