This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.
Moderate· well-documented
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Cranberry products may increase the anticoagulant effect of warfarin. Several cases of increased INR and bleeding have been reported, including one fatality.
Cranberry flavonoids may inhibit CYP2C9, slowing warfarin metabolism. The interaction appears dose-dependent and more significant with cranberry juice concentrate.
Source: Natural Medicines Database · Reviewed April 2026
Cranberry + Warfarin (Coumadin): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Cranberry products may increase the anticoagulant effect of warfarin. Several cases of increased INR and bleeding have been reported, including one fatality.
Cranberry flavonoids may inhibit CYP2C9, slowing warfarin metabolism. The interaction appears dose-dependent and more significant with cranberry juice concentrate.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.