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Harpagophytum procumbens
Moderate· limited-evidence
May be possible under supervision — talk to your prescriber or pharmacist before combining.
Devil's claw may affect blood clotting and interact with warfarin therapy.
Harpagoside may have antiplatelet activity and potentially affect warfarin metabolism.
Source: Natural Medicines Database · Reviewed April 2026
Devil's Claw + Warfarin (Coumadin): use caution. May be possible under supervision — talk to your prescriber or pharmacist before combining. Devil's claw may affect blood clotting and interact with warfarin therapy.
Harpagoside may have antiplatelet activity and potentially affect warfarin metabolism.
Do not stop either abruptly on your own. Talk to your prescriber or pharmacist promptly — bring this page to your appointment.
Educational information only — not medical advice. Always verify with a healthcare professional.