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Lavandula angustifolia
Calculateur gratuit de posologie — doses adultes et enfants selon le poids.
La lavande est une herbe aromatique de la famille des menthe, cultivée depuis plus de 2 500 ans. Elle est largement utilisée en aromathérapie pour ses effets apaisants et a démontré des propriétés anxiolytiques et sédatives dans des études cliniques. L'huile essentielle et les fleurs séchées sont les formes médicinales principales.
Lavender (Lavandula angustifolia) is widely used for anxiety and sleep disorders. Oral standardized lavender oil (Silexan, 80mg) has Level A evidence for generalized anxiety disorder (GAD), with efficacy comparable to lorazepam in some trials. Unlike many botanicals, oral lavender has robust clinical trial data. The anxiolytic effect is mediated by S-lesquel and other constituents interacting with GABA and NMDA receptors. Lavender also has antimicrobial, anti-inflammatory, and analgesic properties.
Essential oil contains linalool (25-38%) and linalyl acetate (25-45%) as primary actives. Silexan (oral preparation) is standardized to these constituents. Linalool is a competitive NMDA receptor antagonist and potentiates GABAergic transmission, explaining anxiolytic effects. It also inhibits voltage-gated calcium channels. Inhalation of lavender oil activates the limbic system via olfactory pathways, affecting autonomic nervous system tone. Topically, it has antimicrobial and anti-inflammatory effects. Linalool and linalyl acetate are rapidly absorbed through skin and mucous membranes.
La lavande est une herbe aromatique de la famille des menthe, cultivée depuis plus de 2 500 ans. Elle est largement utilisée en aromathérapie pour ses effets apaisants et a démontré des propriétés anxiolytiques et sédatives dans des études cliniques. L'huile essentielle et les fleurs séchées sont les formes médicinales principales.
Lavender (Lavandula angustifolia) is widely used for anxiety and sleep disorders. Oral standardized lavender oil (Silexan, 80mg) has Level A evidence for generalized anxiety disorder (GAD), with efficacy comparable to lorazepam in some trials. Unlike many botanicals, oral lavender has robust clinical trial data. The anxiolytic effect is mediated by S-lesquel and other constituents interacting with GABA and NMDA receptors. Lavender also has antimicrobial, anti-inflammatory, and analgesic properties.
Essential oil contains linalool (25-38%) and linalyl acetate (25-45%) as primary actives. Silexan (oral preparation) is standardized to these constituents. Linalool is a competitive NMDA receptor antagonist and potentiates GABAergic transmission, explaining anxiolytic effects. It also inhibits voltage-gated calcium channels. Inhalation of lavender oil activates the limbic system via olfactory pathways, affecting autonomic nervous system tone. Topically, it has antimicrobial and anti-inflammatory effects. Linalool and linalyl acetate are rapidly absorbed through skin and mucous membranes.
Lavender's primary active compounds, linalool and linalyl acetate, exert anxiolytic effects by modulating the GABAergic system. Research suggests these compounds bind to GABA-A receptors in the brain, similar to benzodiazepines, inhibiting nerve transmission and inducing a calming effect. This mechanism is supported by Evidence Level B studies demonstrating efficacy in reducing generalized anxiety.
Yes, lavender can interact with central nervous system (CNS) depressants. Because it possesses sedative properties, taking lavender alongside medications like benzodiazepines, antidepressants, or alcohol may enhance drowsiness and sedation. Additionally, due to potential estrogenic activity, caution is advised for those on hormone therapies. Evidence Level B supports these potential interactions.
For anxiety relief, the standard adult dosage is 80-160 mg of standardized lavender oil (Silexan) taken orally once daily. For sleep aid or mild relaxation, 1-2 cups of lavender flower tea daily is a common traditional dosage. Topical applications should use diluted essential oil to minimize skin irritation risks. Evidence Level B.
Lavender is generally considered unsafe during pregnancy. Oral supplementation and high-dose essential oils are contraindicated due to potential estrogenic effects and the risk of stimulating uterine contractions. While some limited aromatherapy use exists, pregnant individuals should avoid medicinal doses and consult a healthcare provider before use.
Common side effects of oral lavender include headache, nausea, constipation, and increased appetite. Topical application of undiluted essential oil may cause contact dermatitis or skin irritation in sensitive individuals. Those with allergies to the mint family should avoid lavender. Evidence Level B studies report these effects as generally mild.