Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Reduced prostate weight, proliferative index, and expression of AR, SRD5A1, and PSA in rat models [PMID:31873149]; inhibited viability and induced apoptosis in human BPH cells [PMID:32416730].
Suppressed growth and induced apoptosis in LNCaP cells and suppressed tumor growth by up to 80% in xenograft mice [PMID:19476740]; suppressed growth, survival, and invasion of castration-resistant PC3 cells [PMID:24287876].
Potentiated carboplatin effects against ovarian cancer in preclinical models [PMID:24033267] and inhibited ovarian cancer stem cells in vitro [PMID:36178054].
Induced apoptosis in pancreatic cancer cell lines and showed synergistic effects when combined with gemcitabine in vitro and in vivo [PMID:23674070, 29985062].
Flavopereirine lowered cellular viability and induced apoptosis and G2/M-phase cell cycle arrest in CRC cells [PMID:31336690].
Sécurité et effets indésirables
Interactions médicamenteuses
Synthèse des preuves
Sources PubMed
- 1.PMID: 35665643 (2022) — Characterization of alkaloids in bark extracts of Geissospermum vellosii by HPLC-UV-diode array-multistage high-resolution mass spectrometry. · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
- 2.PMID: 31873149 (2019) — Pao Pereira Extract Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by inhibiting 5α-Reductase. · Scientific reports
- 3.PMID: 24033267 (2014) — The plant extract of Pao pereira potentiates carboplatin effects against ovarian cancer. · Pharmaceutical biology
- 4.PMID: 39113866 (2024) — Flavopereirine exerts anti-cancer activities in various human thyroid cancer cells. · American journal of cancer research
- 5.PMID: 19497357