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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Sassafras albidum
A Native American tree that was once the second largest export from the New World, now controversial due to safrole content.
Sassafras albidum is a deciduous tree native to North America, historically used by Native Americans and early settlers as a blood purifier and for skin conditions. Modern use is limited to safrole-free extracts due to the carcinogenicity of safrole, with evidence supporting mild anti-inflammatory and diaphoretic effects. Key compounds include safrole (now restricted), camphor, asarone, and tannins.
Safrole is a methylenedioxybenzene compound that inhibits cytochrome P450 enzymes, particularly CYP2E1, and is metabolized to a hepatocarcinogenic metabolite. Safrole-free extracts may exert anti-inflammatory effects via inhibition of COX-2 and NF-κB pathways. Camphor acts as a mild rubefacient and counterirritant, while tannins provide astringent properties.
A Native American tree that was once the second largest export from the New World, now controversial due to safrole content.
Sassafras albidum is a deciduous tree native to North America, historically used by Native Americans and early settlers as a blood purifier and for skin conditions. Modern use is limited to safrole-free extracts due to the carcinogenicity of safrole, with evidence supporting mild anti-inflammatory and diaphoretic effects. Key compounds include safrole (now restricted), camphor, asarone, and tannins.
Safrole is a methylenedioxybenzene compound that inhibits cytochrome P450 enzymes, particularly CYP2E1, and is metabolized to a hepatocarcinogenic metabolite. Safrole-free extracts may exert anti-inflammatory effects via inhibition of COX-2 and NF-κB pathways. Camphor acts as a mild rubefacient and counterirritant, while tannins provide astringent properties.