These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement or herbal regimen.
Search for a command to run...
Berberis vulgaris
Berberine is an alkaloid found in several plants including barberry, goldenseal, and Oregon grape. It has been used in Ayurvedic and Chinese medicine for over 3,000 years. Modern research has revealed it to be one of the most potent natural compounds for metabolic health, with effects rivaling some pharmaceutical drugs.
| Drug | Severity | Description |
|---|---|---|
| Metformin | moderate | Berberine has similar blood sugar-lowering mechanisms to metformin. Combining them may cause excessive blood sugar reduction (hypoglycemia). |
| Cyclosporine | severe | Berberine significantly increases cyclosporine blood levels (by nearly 100% in one study), increasing risk of toxicity. |
| Losartan | moderate | Berberine may increase losartan levels and its active metabolite, potentially enhancing blood pressure effects. |
| Dextromethorphan | moderate | Berberine may increase dextromethorphan blood levels by inhibiting its metabolism. |