Herbs for Depression & Mood

Evidence-based herbs for depression and mood support. Compare effectiveness, safety, and drug interactions for St. John's Wort, Saffron, and more.

Medical Disclaimer

These herbs are listed for educational purposes only. Effectiveness varies by individual. Always consult your healthcare provider before using herbs, especially if you take medications or have a medical condition.

20 herbs found for this condition

St. John's Wort

Hypericum perforatum

⚠️ Pregnancy/Nursing RiskDepression treatmentWound healingNerve pain relief

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Omega-3 Fish Oil Source

Eicosapentaenoic/Docosahexaenoic acid

Heart diseaseInflammationBrain health

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Curcumin Extract

Curcuma longa (extract)

⚠️ Pregnancy/Nursing RiskAnti-inflammatoryAntioxidantJoint support

Mountain St. John's Wort

Hypericum montanum

⚠️ Pregnancy/Nursing RiskAlpine European folk herbSwiss traditional plantmountain medicine

Kashmiri Saffron

Crocus sativus var. cashmirianus

⚠️ Pregnancy/Nursing Riskmood elevation in Unani medicinecognitive enhancementanti-inflammatory treatment

Lemon Balm

Melissa officinalis

Anxiety reliefSleep aidDigestive soother

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Boswellia Carteri

Boswellia carteri

⚠️ Pregnancy/Nursing RiskSacred incense in Islamic and Christian traditionsAnti-inflammatory for arthritis in Middle Eastern medicineRespiratory and asthma support

Maca

Lepidium meyenii

⚠️ Pregnancy/Nursing RiskEnergy and staminaFertility enhancementHormonal balance

Saffron

Crocus sativus

⚠️ Pregnancy/Nursing RiskDepression treatmentAphrodisiacDigestive aid

Lion's Mane

Hericium erinaceus

⚠️ Pregnancy/Nursing RiskDigestive aidNerve tonicGeneral strengthening

Black Cohosh

Actaea racemosa

⚠️ Pregnancy/Nursing RiskMenstrual pain reliefMenopausal symptom managementRheumatism treatment

Rhodiola

Rhodiola rosea

⚠️ Pregnancy/Nursing RiskStamina and endurance enhancerStress resistanceAltitude sickness prevention

Xiao Yao San Patent

Free and Easy Wanderer

PMSDepressionIrritability

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Bai He Bulb

Lilium brownii

⚠️ Pregnancy/Nursing RiskNourishes lung yinDry cough and respiratory conditionsCalms spirit insomnia

Litsea cubeba

⚠️ Pregnancy/Nursing RiskTraditional Chinese medicine for digestive and heart conditionsUsed in Southeast Asian folk medicine for pain and infections

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African Dream Root

Silene capensis

⚠️ Pregnancy/Nursing RiskDream enhancement for shamanic divinationInitiation into traditional healingRespiratory support

Sceletium

Sceletium tortuosum

⚠️ Pregnancy/Nursing RiskMood enhancement and stress relief by San and Khoikhoi peoplesAnxiety and depression historicallyHunger and thirst suppression on long journeys

Banisteriopsis caapi

⚠️ Pregnancy/Nursing Riskspiritual ceremonydepressionaddiction treatment

Morinda Citrifolia Root

Morinda officinalis

⚠️ Pregnancy/Nursing RiskWarm kidney yangTreat impotenceStrengthen sinews and bones

Rose Petal

Rosa damascena

Emotional support and heart openingDigestive cooling tonicSkin toning in Persian medicine

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Compare These Herbs

See side-by-side comparisons of effectiveness, safety, and interactions.

St. John's Wort vs Omega-3 Fish Oil Source

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